How This Haikou‑based Enterprise Became a Global Hidden Champion in Small‑Molecule Peptides

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Annual Output of 10,000 Tons, Products Sold to 50 Countries: How This Haikou‑based Enterprise Became a Global Hidden Champion in Small‑Molecule Peptides

Competition in the collagen peptide market continues to intensify. As sectors including oral beauty, joint health and sports nutrition keep expanding, upstream raw‑material suppliers are no longer assessed merely on basic supply capacity by end‑product brands. Molecular weight profiles, biological activity, clinical data and regulatory qualifications have become key decision‑making criteria for functional food raw‑material procurement.

Against this backdrop, Hainan Huayan Collagen Technology Co., Ltd. (hereinafter referred to as “Hainan Huayan”), a pioneer in China’s fish collagen peptide industry, has emerged as a representative player drawing on 22 years of technological accumulation and a full‑industrial‑chain layout.

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In October 2026, Hainan Huayan, with 22 years of focus on small‑molecule peptides, will participate in AAES 2026 — Plant Extract Bridge Technology Exhibition & the 17th Plant Extract Bridge Technology Conference (Booth E7, Hall B). It will showcase high‑purity, high‑bioactivity fish collagen peptides and collagen tripeptide raw materials derived from marine organisms, delivering one‑stop full‑category peptide raw‑material solutions for functional foods, nutritional health products and cosmetics.

 

I. Founded in 2005: Pioneering Fish Collagen Peptides in China

Established in 2005 and headquartered in Haikou, Hainan Province, Hainan Huayan Collagen Technology Co., Ltd. is among China’s first enterprises to obtain production permits for fish collagen peptides and a trailblazer in domestic hydrolyzed collagen peptide manufacturing.

To date, Hainan Huayan holds more than 120 invention achievements and boasts an annual production capacity of over 10,000 tons. It has mastered core technologies such as targeted enzymatic hydrolysis and solid‑phase thermal cyclization. Its products have passed 16 internationally authoritative certifications and are exported to more than 50 countries and regions. The company is a globally renowned R&D, manufacturing and full‑solution supplier in the small‑molecule peptide sector.

Strategic investors including Huaxi Yuanyou, South Korea’s NH Fund and Wens Investment have injected capital to fuel corporate growth.

II. Five Core Technologies Redefining Collagen Peptides

  1. Targeted Biological Enzymatic Hydrolysis Technology: Proprietary highly active collagen enzymes enable precise cleavage of native collagen to control molecular weight, granting strong industry competitiveness.
  2. Solid‑Phase Thermal Cyclization Technology: Converts linear protein peptides into stable cyclic structures, markedly improving resistance to protease degradation and biological activity for manufacturing high‑value cyclic collagen dipeptides.
  3. Low‑Temperature Extraction & Triple‑Helix Structure Retention Technology: Gentle proprietary low‑temperature processes fully preserve the triple‑helix structure of native type‑II collagen, securing its core efficacy in inducing oral immune tolerance.
  4. Liposome Encapsulation Technology for Collagen Peptides: Liposome encapsulation or fatty acylation modification protects collagen peptides against gastrointestinal degradation and enhances oral bioavailability and stability.
  5. Whole‑Chain Traceability & Smart Manufacturing: A vertical supply chain covers raw‑material pretreatment, peptide production and finished‑goods manufacturing. Fully enclosed pipeline‑based production minimizes contamination while enabling full‑process traceability.

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III. Core Product Portfolio

Leveraging the above‑mentioned technological system, Hainan Huayan will highlight the following products at the exhibition:

  1. Fish Collagen Peptides: One of China’s first licensed products of this kind. Produced via targeted biological enzymatic hydrolysis with controllable molecular weight (2000‑3000 Da). Features high purity, high absorption rate and low allergenicity, complying with regulatory requirements and export standards across multiple countries.
  2. Collagen Tripeptides: High‑value‑added flagship raw material with an extremely low average molecular weight (<500 Da). Easy‑to‑absorb and highly bioactive. The company participated in formulating the group standard Collagen Tripeptides (T/CI 487‑2024), making it a high‑end market benchmark.
  3. Native Type‑II Collagen: Manufactured with proprietary low‑temperature extraction to retain intact triple‑helix conformation and biological activity. A low daily dosage of 40 mg induces oral immune tolerance. Clinical trials conducted by Qingdao Central Hospital of Kangfu University (2026) demonstrate promising effects for middle‑aged and elderly knee joint health with favorable safety profiles. Suitable for populations concerned with joint health, sports injuries and senior‑care nutrition.
  4. Cyclic Collagen Dipeptides: Produced through solid‑phase thermal cyclization. Possess unique cyclic structures together with biological activities including neuroprotection and immune enhancement, delivering differentiated raw‑material options for functional food and pharmaceutical applications.
  5. Full‑Category Peptide Raw‑Material OEM / ODM Services: A comprehensive portfolio of marine, terrestrial and plant‑sourced polypeptides (fish, sea cucumber, oyster, corn, pea, soybean and more). One‑stop customized services ranging from raw‑materials to end‑consumer finished products are available.

IV. Co‑building Industry Standards, Creating Shared Value with Partners

As an industry pioneer, Hainan Huayan has deeply participated in drafting national, industrial and group standards for collagen peptides. In industry‑university‑research collaboration, it has built joint laboratories with institutions such as Ocean University of China and undertaken multiple key national, provincial and municipal R&D projects, including the 10‑million‑RMB Haikou Major Science and Technology Program “Research and Application Demonstration on Key Preparation Technologies for Neuroprotective Peptides Derived from Tilapia‑Scale Collagen”.

The company also cooperates with well‑known brands such as Mengniu. Joint project teams, sample testing and pilot‑scale trials are carried out for functional dairy R&D to co‑develop next‑generation weight‑management and wellness products.

At this exhibition, Hainan Huayan looks forward to in‑depth exchanges with brand owners of functional foods, health foods and foods for special medical purposes, OEM/ODM enterprises, as well as R&D directors and product managers from beauty skincare, sports nutrition and pet nutrition sectors. Potential cooperation includes customized raw‑material supply, joint R&D and technical tackling, one‑stop OEM/ODM services, functional validation and marketing‑claim collaboration, as well as brand co‑creation and product upgrading supported by clinical data.

We welcome you to visit Booth E7, Hall B in October 2026 for communication and cooperation.


Post time: Aug-27-2026

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