Research progress of bioactive peptides prepared by whey protein enzymatic hydrolysis

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Whey protein is the soluble protein obtained by removing casein from raw milk. It contains various active proteins such as β-lactoglobulin (β-LG), α-lactalbumin (α-La), immunoglobulin (IB), and lactoferrin (LF), with a rich amino acid composition [1]. Due to its complete variety of essential amino acids, an amino acid composition pattern similar to that of humans, easy digestion and absorption, it has a high biological value.

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As functional fragments of proteins, bioactive peptides (BAPs) possess multiple physiological functions and have become a research hotspot in the 21st century. The biological activities of BAPs are related to their amino acid composition, sequence, and structure. They can be directly digested and absorbed by the human intestine and enter the circulatory system in their complete form, thus exhibiting high bioavailability. The length and sequence of peptide fragments determine their activity and affinity for receptors, allowing them to rapidly enter the blood circulatory system to exert systemic physiological effects . The most prominent advantage of BAPs is that their metabolites are amino acids, offering higher safety compared to chemically synthesized drugs.

1. Antioxidant peptides

Antioxidant peptides can directly scavenge reactive oxygen species (ROS); inhibit ROS production by chelating pro-oxidant metal ions and reducing the levels of ROS-generating oxidases; and exert cytoprotective effects by anti-inflammation, regulating cell apoptosis, activating autophagy, and enhancing stress resistance, thereby rapidly restoring the normal redox balance in the body. In recent years, many scholars at home and abroad have studied the functions and applications of antioxidant peptides in whey protein.

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2. ACE inhibitory peptides

ACE inhibitory peptides)can lower blood pressure by inhibiting the biological activity of ACE. ACE inhibitory peptides not only regulate the intestinal microbiota and reduce the probability of intestinal diseases but also achieve blood pressure reduction through their specific effects. Due to their rich probiotic functions, they are favored by a wide range of consumers.

Whey protein is not only an important source of nutrients, but the active proteins and BAPs (bioactive peptides) it contains exhibit multiple biological functions, such as antioxidant activity, blood glucose regulation, antibacterial effect, etc. Hainan Huayan Collagen is an excellent whey protein peptide supplier, we have a big collagen factory adn advanced technology laboratory, so competitive price and high quality can be provided.

 


Post time: May-27-2025

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